Occupational mercury and arsenic toxicology. Mercury: chemical forms (elemental vapor, inorganic salts, methylmercury), neurological effects (tremor, erethism), nephrotoxicity, biomarkers, chelation. Arsenic: occupational exposure (smelting, semiconductor), dermatologic findings (hyperkeratosis, Mees lines), peripheral neuropathy, and arsenic-related cancers.
A patient with chronic exposure to inorganic arsenic presents with skin findings. Which of the following best describes the characteristic dermatologic triad used as clinical markers of chronic arsenicism?